Florence, Mougel

Lecturer, PhD 1997

Tel. 33 1 69 15 64 93
Mail. florence.mougel-imbert@universite-paris-saclay.fr

RESEARCH TOPICS

My present research focuses on mechanisms of adaptation an dis based on two biological models:

  • Parasitoid insects belonging to the Cotesia genus for which I study the components of reproductive success, in particular the ones related to host adaptation
  • hematophagous bugs vector of the Chagas disease belonging the genus Triatoma and Rhodnius for which I’m interested in adaptation to anthropic environment.

I develop genetic tools (mapping based on neutral markers, identification of QTL), genomics (assembly and identification of interesting genes) and transcriptomics (differential expression analysis).

TEACHING

Topics:

  • Diversity and Evolution of living organisms
  • Biological cycle and development
  • Genetics
  • Statistics

Development of interactive exercises:

PUBLICATIONS

Gornard, S., Mougel, F., Germon, I., Borday-Birraux, V., Venon, P., Drabo, S., & Kaiser, L. (2024). Cellular dynamics of host − parasitoid interactions: Insights from the encapsulation process in a partially resistant host. Journal of Insect Physiology, 155, 104646. https://doi.org/10.1016/j.jinsphys.2024.104646
Gornard, S., Germon, I., Borday-Birraux, V., Dulac, C. C., Kaiser-Arnauld, L. M.-P., & Mougel, F. (2023). Revealing insect resistance mechanisms in a host-parasitoid interaction. Hellenic Entomological Society. https://mnhn.hal.science/mnhn-04571119
Gornard, S., Mougel, F., & Kaiser-Arnauld, L. M.-P. (2023, October). Interaction between the parasitoid Cotesia typhae and its host Sesamia nonagrioides : insights into virulence and resistance traits. XII European Congress of Entomology. https://mnhn.hal.science/mnhn-04571101
Bressac, C., El Sabrout, A., Kifouche, F., Anne, M., Capdevielle-Dulac, C., Mougel, F., & Kaiser, L. (2023). Hot and cold waves decrease sperm production and bias sex ratio in the parasitoid wasp Cotesia typhae (Hymenoptera, Braconidae). Journal of Insect Physiology, 149, 104553. https://doi.org/10.1016/j.jinsphys.2023.104553
Fortuna, T. M., Anne, M., Le Gonnidec, M., Jeannette, R., Bressac, C., Rebaudo, F., Mougel, F., & Kaiser, L. (2023). Susceptibility to cold suggests low risk of establishment of a tropical parasitoid attacking the corn pest Sesamia nonagrioides. Biological Control, 186, 105359. https://www.sciencedirect.com/science/article/pii/S1049964423002128
Germon, I., Delachanal, C., Mougel, F., Martnand-Mari, C., Debiais-Thibaud, M., & Borday-Birraux, V. (2023). Interference with the retinoic acid signalling pathway inhibits the initiation of teeth and caudal primary scales in the small-spotted catshark Scyliorhinus canicula. PeerJ. https://doi.org/10.7717/peerj.15896
Muller, H., Heisserer, C., Fortuna, T., Mougel, F., Huguet, E., Kaiser, L., & Gilbert, C. (2022). Investigating bracovirus chromosomal integration and inheritance in lepidopteran host and nontarget species. Molecular Ecology, 31(21), 5538–5551. https://doi.org/10.1111/mec.16685
Capdevielle Dulac, C., Benoist, R., Paquet, S., Calatayud, P.-A., Obonyo, J., Kaiser, L., & Mougel, F. (2022). Spontaneous parthenogenesis in the parasitoid wasp Cotesia typhae: low frequency anomaly or evolving process? Peer Community Journal, 2, e37. https://doi.org/10.24072/pcjournal.135
Filée, J., Merle, M., Bastide, H., Mougel, F., Bérenger, J.-M., Folly-Ramos, E., Almeida, C. E., & Harry, M. (2022). Phylogenomics for Chagas disease vectors of the Rhodnius genus (Hemiptera, Triatominae): what we learn from mito-nuclear conflicts and recommendations. Frontiers in Ecology and Evolution, 9. https://www.frontiersin.org/articles/10.3389/fevo.2021.750317
Merle, M., Filée, J., De Oliveira, J., Almeida, C. E., Mougel, F., Bastide, H., Girondot, M., Da Rosa, J. A., & Harry, M. (2022). Genome size variation of Chagas disease vectors of the Rhodniini tribe. The American Journal of Tropical Medicine and Hygiene, 107(1), 211–215. https://doi.org/10.4269/ajtmh.21-0394
Marchant, A., Mougel, F., Jacquin-Joly, E., Almeida, C. E., Blanchet, D., Bérenger, J.-M., Da Rosa, J. A., & Harry, M. (2021). Chemosensory Gene Expression for Two Closely Relative Species Rhodnius robustus and R. prolixus (Hemiptera, Reduviidade, Triatominae) Vectors of Chagas Disease. Frontiers in Ecology and Evolution, 9, 725504. https://doi.org/10.3389/fevo.2021.725504
Alford, L., Louâpre, P., Mougel, F., & Van Baaren, J. (2020). Measuring the evolutionary potential of a winter-active parasitic wasp to climate change. Oecologia, 194(1–2), 41–50. https://doi.org/10.1007/s00442-020-04761-2
Benoist, R., Capdevielle‐Dulac, C., Chantre, C., Jeannette, R., Calatayud, P., Drezen, J., Dupas, S., Le Rouzic, A., Le Ru, B., Moreau, L., Van Dijk, E., Kaiser, L., & Mougel, F. (2020). Quantitative trait loci involved in the reproductive success of a parasitoid wasp. Molecular Ecology, 29(18), 3476–3493. https://doi.org/10.1111/mec.15567
Benoist, R., Paquet, S., Decourcelle, F., Guez, J., Jeannette, R., Calatayud, P.-A., Le Ru, B., Mougel, F., & Kaiser, L. (2020). Role of egg-laying behavior, virulence and local adaptation in a parasitoid’s chances of reproducing in a new host. Journal of Insect Physiology, 120, 103987. https://doi.org/10.1016/j.jinsphys.2019.103987
Benoist, R., Chantre, C., Capdevielle-Dulac, C., Bodet, M., Mougel, F., Calatayud, P. A., Dupas, S., Huguet, E., Jeannette, R., Obonyo, J., Odorico, C., Silvain, J. F., Le Ru, B., & Kaiser, L. (2017). Relationship between oviposition, virulence gene expression and parasitism success in Cotesia typhae nov. sp. parasitoid strains. Genetica, 145(6), 469–479. https://doi.org/10.1007/s10709-017-9987-5
Marchant, A., Mougel, F., Jacquin-Joly, E., Costa, J., Almeida, C. E., & Harry, M. (2016). Under-Expression of Chemosensory Genes in Domiciliary Bugs of the Chagas Disease Vector Triatoma brasiliensis. PLOS Neglected Tropical Diseases, 10(10), e0005067. https://doi.org/10.1371/journal.pntd.0005067
Arca, M., Mougel, F., Guillemaud, T., Dupas, S., Rome, Q., Perrard, A., Muller, F., Fossoud, A., Capdevielle-Dulac, C., Torres-Leguizamon, M., Chen, X. X., Tan, J. L., Jung, C., Villemant, C., Arnold, G., & Silvain, J.-F. (2015). Reconstructing the invasion and the demographic history of the yellow-legged hornet, Vespa velutina, in Europe. Biological Invasions, 17(8), 2357–2371. https://doi.org/10.1007/s10530-015-0880-9
Bertrand, B., Alburaki, M., Legout, H., Moulin, S., Mougel, F., & Garnery, L. (2015). MtDNA COI-COII marker and drone congregation area: An efficient method to establish and monitor honeybee ( Apis mellifera L.) conservation centres. Molecular Ecology Resources, 15(3), 673–683. https://doi.org/10.1111/1755-0998.12339
Marchant, A., Mougel, F., Almeida, C., Jacquin-Joly, E., Costa, J., & Harry, M. (2015). De novo transcriptome assembly for a non-model species, the blood-sucking bug Triatoma brasiliensis, a vector of Chagas disease. Genetica, 143(2), 225–239. https://doi.org/10.1007/s10709-014-9790-5
Marchant, A., Mougel, F., Mendonça, V., Quartier, M., Jacquin-Joly, E., da Rosa, A., Petit, E., & Harry, M. (2015). Comparing de novo and reference-based transcriptome assembly strategies by applying them to the blood-sucking bug Rhodnius prolixus. Insect Biochemistry and Molecular Biology. https://doi.org/10.1016/j.ibmb.2015.05.009
Arca, M., Papachristoforou, A., Mougel, F., Rortais, A., Monceau, K., Bonnard, O., Tardy, P., Thiéry, D., Silvain, J.-F., & Arnold, G. (2014). Defensive behaviour of Apis mellifera against Vespa velutina in France: Testing whether European honeybees can develop an effective collective defence against a new predator. Behavioural Processes, 106, 122–129. https://doi.org/10.1016/j.beproc.2014.05.002
Mougel, F., Poursat, M.-A., Beaume, N., Vautrin, D., & Solignac, M. (2014). High-resolution linkage map for two honeybee chromosomes: the hotspot quest. Molecular Genetics and Genomics, 289(1), 11–24. https://doi.org/10.1007/s00438-013-0784-2
Monceau, K., Arca, M., Leprêtre, L., Mougel, F., Bonnard, O., Silvain, J.-F., Maher, N., Arnold, G., & Thiéry, D. (2013). Native Prey and Invasive Predator Patterns of Foraging Activity: The Case of the Yellow-Legged Hornet Predation at European Honeybee Hives. PLoS ONE, 8(6), e66492. https://doi.org/10.1371/journal.pone.0066492
Arca, M., Capdevielle-Dulac, C., Villemant, C., Mougel, F., Arnold, G., & Silvain, J.-F. (2012). Development of microsatellite markers for the yellow-legged Asian hornet, Vespa velutina, a major threat for European bees. Conservation Genetics Resources, 4(2), 283–286. https://doi.org/10.1007/s12686-011-9525-1
Mougel, F., Solignac, M., Vautrin, D., Baudry, E., Ogden, J., Tchapla, A., Schweitz, H., & Gilbert, H. (2012). Quantitative traits loci (QTL) involved in body colour, wing morphometry, cuticular hydrocarbons and venom components in honeybee. Apidologie, 43(2), 162–181. https://doi.org/10.1007/s13592-011-0090-0
Bessoltane, N., Toffano-Nioche, C., Solignac, M., & Mougel, F. (2012). Fine Scale Analysis of Crossover and Non-Crossover and Detection of Recombination Sequence Motifs in the Honeybee (Apis mellifera). PLoS ONE, 7(5), e36229. https://doi.org/10.1371/journal.pone.0036229
Solignac, M., Mougel, F., Vautrin, D., Monnerot, M., & Cornuet, J. M. (2007). A third-generation microsatellite-based linkage map of the honey bee, Apis mellifera, and its comparison with the sequence-based physical map. Genome Biol, 8(4), R66. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17459148
Solignac, M., Zhang, L., Mougel, F., Li, B., Vautrin, D., Monnerot, M., Cornuet, J.-M., Worley, K. C., Weinstock, G. M., & Gibbs, R. A. (2007). The genome of Apis mellifera: dialog between linkage mapping and sequence assembly. Genome Biology, 8(3), 403. https://doi.org/10.1186/gb-2007-8-3-403
Beye, M., Gattermeier, I., Hasselmann, M., Gempe, T., Schioett, M., Baines, J. F., Schlipalius, D., Mougel, F., Emore, C., Rueppell, O., Sirvio, A., Guzman-Novoa, E., Hunt, G., Solignac, M., & Page Jr., R. E. (2006). Exceptionally high levels of recombination across the honey bee genome. Genome Res, 16(11), 1339–1344. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17065604
Mougel, F., Manichanh, C., N’Guyen, G. D., & Termier, M. (2004). Genomic Choice of Codons in 16 Microbial Species. Journal of Biomolecular Structure and Dynamics, 22(3), 315–329. https://doi.org/10.1080/07391102.2004.10507003
Baudry, E., Kryger, P., Allsopp, M., Koeniger, N., Vautrin, D., Mougel, F., Cornuet, J. M., & Solignac, M. (2004). Whole-Genome Scan in Thelytokous-Laying Workers of the Cape Honeybee (Apis mellifera capensis): Central Fusion, Reduced Recombination Rates and Centromere Mapping Using Half-Tetrad Analysis. Genetics, 252(May), 243–252. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15166151
Solignac, M., Vautrin, D., Baudry, E., Mougel, F., Loiseau, A., & Cornuet, J. M. (2004). A Microsatellite-Based Linkage Map of the Honeybee, Apis mellifera L. Genetics, 262(May), 253–262. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15166152
Solignac, M., Vautrin, D., Loiseau, A., Mougel, F., Baudry, E., Estoup, A., Garnery, L., Haberl, M., & Cornuet, J.-M. (2003). Five hundred and fifty microsatellite markers for the study of the honeybee (Apis mellifera L.) genome. Mol Ecol Notes, 3, 307–311.
Queney, G., Ferrand, N., Weiss, S., Mougel, F., & Monnerot, M. (2001). Stationary Distributions of Microsatellite Loci Between Divergent Population Groups of the European Rabbit (Oryctolagus cuniculus). Molecular Biology and Evolution, 18(12), 2169–2178. https://doi.org/10.1093/oxfordjournals.molbev.a003763
Ferrand, N., Azevedo, M., & Mougel, F. (2000). A diallelic short tandem repeat (CCCCG)4 or 5, located in intron 1 of rabbit α-globin gene. Animal Genetics, 31(1), 74–75. https://doi.org/10.1111/j.1365-2052.2000.579-9.x
Queney, G., Ferrand, N., Marchandeau, S., Azevedo, M., & Mougel, F. (2000). Absence of a genetic bottleneck in a wild rabbit (Oryctolagus cuniculus) population exposed to a severe viral epizootic. Molecular Ecology.
Van Der Loo, W., Mougel, F., Sánchez, M. S., Bouton, C., Castien, E., Fonseca, A., Ferrand, N., Soriguer, R., & Monnerot, M. (1999). Cytonuclear disequilibria in wild populations of rabbit ( Oryctolagus cuniculus L. ) suggest unequal allele turnover rates at the b locus ( IGKC1 ). Immunogenetics, 49(7–8), 629–643. https://doi.org/10.1007/s002510050659
Van Der Loo, W., Mougel, F., Bouton, C., Sanchez, M. S., & Monnerot, M. (1999). The allotypic patchwork pattern of the rabbit IGKC1 allele b5wf : genic exchange or common ancestry? Immunogenetics, 49(1), 7–14. https://doi.org/10.1007/s002510050458
Mougel, F., Mounolou, J. C., & Monnerot, M. (1997). Nine polymorphic microsatellite loci in the rabbit, Oryctolagus cuniculus. Animal Genetics, 28(1), 58–71. https://doi.org/10.1111/j.1365-2052.1997.00047.x
Van Der Loo, W., Bouton, C. E., Sanchez, M., Mougel, F., Castién, E., Hamers, R., & Monnerot, M. (1995). Characterization and DNA sequence of the b6w2 allotype of the rabbit immunoglobulin kappa 1 light chain (b locus). Immunogenetics, 42(5), 333–341. https://doi.org/10.1007/BF00179394
Monnerot, M., Vigne, J.-D., Biju-Duval, C., Casane, D., Callou, C., Mougel, F., Soriguer, R., Dennebouy, N., & Mounolou, J.-C. (1994). Rabbit and man: genetic and historic approach. Genet Sel Evol, 167s–182s.
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